No2-3(2) 2019
Back to the issue
DOI 10.37219/2528-8253-2019-2-58 |
Bezshapochny S, Hychak I
Optimal therapy of inflammatory diseases in the risk groups |
Bezshapochny Sergey B.
Ukrainian Medical Stomatological Academy
Head of Department of oto-rhino-laryngology with ophthalmology
Doctor of Medical Sciences, Professor.
Email: bezshapochny@ukr.net
Hychak Irina
Ukrainian Medical Stomatological Academy
Department of oto-rhino-laryngology with ophthalmology
E-mail: irinagrishina@yahoo.com |
Abstract
Topicality: Pregnant women are at increased risk of susceptibility to
inflammatory diseases of the pharynx.
Unfortunately, there are currently no approved protocols for the treatment
of ENT diseases for such patients in Ukraine. It is very important to choose
a safe and effective drug with minimal absorption in to the general blood
flow. Another important point for the doctors the legal aspect, namely, the
absence of contraindications to the appointment of pregnant women in the
instructions for use of the medicine. These criteria are met by Celista
spray for a throat, which is based on the active substance miramistin (0.1
mg/ml).
Materials and methods: We conducted a study that involved 30 pregnant
women. These lection criteria were pregnant women from I to III trimester
with a diagnosis of acute pharyngitis / tonsillitis / tonsillopharyngitis,
up to 5 days after the disease, 0-3 points on a modified McAizek-Center
scale, voluntary consent and adequate attitude to the study. All patients
were prescribed topical irrigation of Celista spray x 4 times a day. The
examination complex included subjective assessment of the condition on a
10-point visual-analogue scale, symptom severity assessment was performed
using a questionnaire on a 4-point scale by criteria such as sore throat,
burning, coughing (0 – no symptom, 1 – the symptom is poorly expressed, 2 –
the symptom is moderately expressed, 3 – the symptom is strongly expressed).
Objective examination included assessment of the condition by criteria such
as hyperemia of the posterior pharyngeal wall; hypertrophy of the follicles
of the posterior wall of the pharynx; hypertrophy and swelling of the
tonsils; regional lymphadenitis for 0; 3; 5; 7 days.
Results: It was found that the pain index decreased by 1.6 points,
laceration in the throat – by 1.78 points, cough – by 0.3 points after
treatment. A similar tendency was observed in the objective status:
hyperemia of the posterior pharyngeal wall decreased by 1.5 points,
hypertrophy of the pharynx follicles – by 1.27 points, hyperemia and
swelling of the tonsils – by 0.8 points, regional lymphadenitis – by 0.5
points.
Conclusion: Thus, given that the absorption of Celista spray is
actually absent, the drug has no contraindications for prescription during
pregnancy, and based on our results, we can confirm the effectiveness of its
use during pregnancy for the local treatment of acute inflammatory diseases
of the pharynx in pregnant women in any period. |
Keywords
pharyngitis, tonsillitis, pregnancy, miramistin, celista. |
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